发明名称 |
HYDROPHOBIC INTERACTION CHROMATOGRAPHY PURIFICATION OF FACTOR VII POLYPEPTIDES |
摘要 |
The invention described herein provides new methods of preparing purified Factor VII polypeptide drug substances in large quantities (industrial scale levels) that are associated with reduced content of product-related impurities (e.g., late eluting peaks) and/or that exhibit a relatively uniform glycosylation pattern.
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申请公布号 |
US2011064719(A1) |
申请公布日期 |
2011.03.17 |
申请号 |
US20100884927 |
申请日期 |
2010.09.17 |
申请人 |
NOVO NORDISK A/S |
发明人 |
RASMUSSEN DANIEL E.;KRARUP JANUS |
分类号 |
A61K38/48;C07K14/745;C12N9/64;C12P21/00 |
主分类号 |
A61K38/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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