发明名称 LINKER COMPOUND, LIGAND COMPLEX AND PROCESS FOR PRODUCING THEM
摘要 The present invention provides a novel linker compound which minimizes any nonspecific hydrophobic interactions and is capable of easily adjusting the length to a disulfide group subjected to metal bond to thereby enable effective formation of a metal-sulfur bond; novel ligand conjugate and ligand carrier, and a process for producing them. The linker compound is of a structure represented by the following general formula (1) (see formula 1) where a, b, d, e are independently an integer of 0 to 6. X has a structure serving as a multi-branched structure moiety including three or more hydrocarbon derivative chains, wherein the hydrocarbon derivative chains each include an aromatic amino group at an end thereof, and may or may not include a carbon-nitrogen bond in a main chain thereof. The ligand conjugate includes the linker compound having a sugar molecule introduced therein.
申请公布号 CA2559962(C) 申请公布日期 2011.03.15
申请号 CA20052559962 申请日期 2005.02.04
申请人 JAPAN SCIENCE AND TECHNOLOGY AGENCY;NATIONAL UNIVERSITY CORPORATION KAGOSHIMA UNIVERSITY 发明人 SUDA, YASUO;ARANO, AKIO;KUSUMOTO, SHOICHI;SOBEL, MICHAEL;WAKAO, MASAHIRO
分类号 C07D339/04;C07H15/04;G01N33/543 主分类号 C07D339/04
代理机构 代理人
主权项
地址