发明名称 LPA RECEPTOR AGONISTS AND ANTAGONISTS AND METHODS OF USE
摘要 The present invention relates to compounds according to formula (I) as disclosed herein as well as pharmaceutical compositions which include those compounds. Also disclosed are methods of using such compounds, which have activity as agonists or as antagonists of LPA receptors; such methods including inhibiting LPA activity on an LPA receptor, modulating LPA receptor activity, treating cancer, enhancing cell proliferation, and treating a wound. (see formula I)
申请公布号 CA2402038(C) 申请公布日期 2011.03.15
申请号 CA20012402038 申请日期 2001.03.19
申请人 THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION 发明人 MILLER, DUANE D.;TIGYI, GABOR;DALTON, JAMES T.;SARDAR, VINEET M.;ELROD, DON B.;XU, HUIPING;BAKER, DANIEL L.;WANG, DE-AN;LILIOM, KAROLY;FISCHER, DAVID J.;VIRAG, TAMAS;NUSSER, NORA;SUN, GUOPING
分类号 C07F9/06;C12N15/09;A61K31/27;A61K31/66;A61K31/685;A61P17/02;A61P35/00;A61P43/00;C07F9/09;C07F9/10;C07F9/11;C07F9/17;C07F9/22;C07F9/38;C07F9/40;C07F9/6506;C07F9/6571;C07F9/6584 主分类号 C07F9/06
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