发明名称 |
COMPOUNDS FOR TREATING OR PREVENTING AMINE OXIDASE RELATED DISEASES OR DISORDERS |
摘要 |
This invention relates to small interfering RNAs (siRNAs) that down regulates the expression of vascular adhesion protein 1 (VAP-1) for prevention or treatment of a disease or disorder that benefits from the inhibition or down regulation of VAP-1. Pharmaceutical compositions comprising said siRNAs in combination with pharmaceutically acceptable carriers are also included. Furthermore, the invention concerns expression vectors comprising nucleic acids encoding the siRNA duplexes or the antisense strands of said duplexes in a manner which allows expression of said siRNA duplexes or antisense strands within a mammalian cell. Pharmaceutical compositions comprising said expression vectors in combination with pharmaceutically acceptable carriers are also included.
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申请公布号 |
US2011038922(A1) |
申请公布日期 |
2011.02.17 |
申请号 |
US20060917638 |
申请日期 |
2006.06.12 |
申请人 |
FARON PHARMACEUTICALS OY (A FINNISH COMPANY) |
发明人 |
JALKANEN SIRPA;JALKANEN MARKKU;SALMI MARKO |
分类号 |
A61K9/127;A61K31/7105;C12N;C12N15/113;C12N15/63 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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