发明名称 PROCESS OF PREPARING 2,2'-(1-METHYL-1,2-ETHANEDIYLIDENE)BIS[HYDRAZINE CARBOXIMIDAMIDE]
摘要 Process for the preparation of 2,2'-(1-methyl-1,2-ethanediylidene)bis[hydrazine carboximidamide] by: a) reacting aminoguanidine hydrochloride with methylglyoxal aldehyde or methylglyoxal dimethyl acetal; and b) purifying the 2,2'-(1-methyl-1,2-ethanediylidene)bis[hydrazine carboximidamide] by crystallization from an acidic aqueous-isopropyl alcohol medium.
申请公布号 WO9745110(A1) 申请公布日期 1997.12.04
申请号 WO1997US08347 申请日期 1997.05.19
申请人 SANOFI;PHILION, RICHARD;ELENBAAS, STEVEN, A. 发明人 PHILION, RICHARD;ELENBAAS, STEVEN, A.
分类号 A61K31/155;A61K31/00;A61P35/00;C07C281/10;C07C281/18;(IPC1-7):A61K31/155;C07C277/08;C07C279/00 主分类号 A61K31/155
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