MONOCLONAL ANTIBODY FOR DISCRIMINATING AND DETECTING ABNORMAL PRION CAUSING CHRONIC WASTING DISEASE

摘要

PURPOSE: A monoclonal antibody for specifically identifying and detecting abnormal prion of chronic wasting disease is provided. CONSTITUTION: A fusion cell line of deposit number KCLRF-BP-00214 produces a monoclonal antibody for detecting abnormal prion of chronic wasting disease. A method for preparing fusion cell line comprises: a step of inoculating a peptide of sequence number 1 to knock-out mouse; a step of isolating B cells from the mouse; and a step of fusing the B cells with mouse myeloma cells. The monoclonal antibody is used for detecting the abnormal prion through western blotting.