USE OF PKC INHIBITORS FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF AUTOIMMUNE DISEASES

摘要

Methods for inhibiting activation and/or proliferation of T cells and B cells and for treating autoimmune diseases and/or disease manifestations are disclosed, particularly using the isozyme selective PKC inhibitor, (S)-3,4-¢N,N'-1,1'-((2''-ethoxy)-3'''(O)-4'''-(N,N-dimethylamino)-butane)-bis-(3,3'-indolyl)!-1(H)-pyrrole-2,5-dione and its pharmaceutically acceptable salts.