发明名称 ANALYZING THE FMR1 GENE
摘要 A method of predicting a degree of risk of early ovarian aging of a young female. The method includes analyzing the female's FMR1 gene, wherein the FMR1 gene has a first allele and a second allele; determining the number of triple CGG repeats on each of the first and second alleles; defining a normal range of triple CGG repeats; comparing the number of triple CGG repeats on each of the first and second alleles to the normal range. If the triple CGG repeat numbers for both of the first and second alleles are within the normal range, then the female is at minimal risk for early ovarian aging. If the triple CGG repeat number for one of the first and second alleles is outside of the normal range and the other one of the first and second alleles is within the normal range, then the first and second alleles are heterozygous and the female is at increased risk for early ovarian aging. If the triple CGG repeat numbers for both of the first and second alleles are outside of the normal range, then the first and second alleles are homozygous and the female is also at an increased risk for early ovarian aging.
申请公布号 CA2768667(A1) 申请公布日期 2011.01.27
申请号 CA20102768667 申请日期 2010.07.23
申请人 GLEICHER, NORBERT;BARAD, DAVID H. 发明人 GLEICHER, NORBERT;BARAD, DAVID, H.;BARAD, DAVID H.
分类号 C12Q1/68 主分类号 C12Q1/68
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