| 发明名称 |
CHIMÄRE ADENOVIREN ZUR VERWENDUNG IN DER KREBSBEHANDLUNG |
| 摘要 |
<p>The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.</p> |
| 申请公布号 |
AT491799(T) |
申请公布日期 |
2011.01.15 |
| 申请号 |
AT20050753804T |
申请日期 |
2005.05.24 |
| 申请人 |
BAYER SCHERING PHARMA AKTIENGESELLSCHAFT |
发明人 |
HARDEN, PAUL;HERMISTON, TERRY;KUHN, IRENE |
| 分类号 |
C12N15/861;A61K35/76;A61K48/00;C12N7/00;C12N7/01;C12N7/02 |
主分类号 |
C12N15/861 |
| 代理机构 |
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