发明名称 |
VARIANTS OF PLASMINOGEN AND PLASMIN |
摘要 |
The invention relates to variants of plasminogen and plasmin comprising one or more point mutations in the catalytic domain which reduce or prevent autocatylic destruction of the protease activity of plasmin. Compositions, uses and methods of using said variants of plasminogen and plasmin are also disclosed. |
申请公布号 |
WO2011004011(A1) |
申请公布日期 |
2011.01.13 |
申请号 |
WO2010EP59902 |
申请日期 |
2010.07.09 |
申请人 |
THROMBOGENICS NV;ZWAAL, RICHARD REINIER |
发明人 |
ZWAAL, RICHARD REINIER |
分类号 |
C07K14/47;A61K38/48;C12N9/68;C12N15/11 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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