发明名称 |
In vitro method for identifying a compound using an eukaryotic mechanosensory transduction channel |
摘要 |
The present invention provides, for the first time, nucleic acids encoding a eukaryotic mechanosensory transduction channel (MSC) protein. The proteins encoded by these nucleic acids form channels that can directly detect mechanical stimuli and convert them into electrical signals. These nucleic acids and the proteins they encode can be used as probes for sensory cells in animals, and can be used to diagnose and treat any of a number of human conditions involving inherited, casual, or environmentally-induced loss of mechanosensory transduction activity.
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申请公布号 |
US7867721(B2) |
申请公布日期 |
2011.01.11 |
申请号 |
US20070703343 |
申请日期 |
2007.02.06 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
ZUKER CHARLES S.;WALKER RICHARD G.;WILLINGHAM AARRON |
分类号 |
G01N33/53;C07K14/00;C07K14/435;C12N5/00;C12N15/12 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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