发明名称 Purification of streptococcal capsular polysaccharide
摘要 <p>A purification process for the capsular polysaccharide of S.agalactiae in which the saccharide is initially treated with an aqueous mixture of an alcohol and a calcium salt, followed by precipitation with a cationic detergent. The process can be completed in less than three days and has a yield of around 60%. It avoids the need for DNase, RNase and/or protease treatment. The saccharides of the process have a very low protein contamination and a very low absorbance at 280nm.</p>
申请公布号 EP2270056(A2) 申请公布日期 2011.01.05
申请号 EP20100179778 申请日期 2006.02.01
申请人 NOVARTIS VACCINES AND DIAGNOSTICS S.R.L. 发明人 COSTANTINO, PAOLO
分类号 C08B37/00;C12P19/04 主分类号 C08B37/00
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