HYPOCHOLESTEROLIMIC COMPOSITIONS COMPRISING LINALOOL

摘要

PURPOSE: A composition for reducing cholesterol containing linalool is provided to reduce expression of HMG-CoA reductase which relates to cholesterol biosynthesis. CONSTITUTION: A composition for reducing cholesterol contains linalool as an active ingredeint. The composition reduces the expression of SREBP, SCAP, and S1P expression and also reduces cholesterol content by increasing Insig-1 gene expression. A pharmaceutical composition for preventing and treating hyperlipidemia contains the composition for reducing cholesterol as an active ingredient. A pharmaceutical composition for preventing and treating arteriosclerosis contains the composition for reducing cholesterol as an active ingredient.