| 发明名称 |
AURISTATIN DRUG LINKER CONJUGATES |
| 摘要 |
Drug Linker compounds and Drug Linker Ligand conjugates are provided that have auristatins linked via the C-terminus. The conjugates show efficacy without the need for a self-immolative group to release the drug. |
| 申请公布号 |
EP2265283(A1) |
申请公布日期 |
2010.12.29 |
| 申请号 |
EP20090721267 |
申请日期 |
2009.03.18 |
| 申请人 |
SEATTLE GENETICS, INC. |
发明人 |
SENTER, PETER;DORONINA, SVETLANA;BOVEE, TIMOTHY |
| 分类号 |
A61K47/48;A61K39/00;C07K17/00;C07K17/14 |
主分类号 |
A61K47/48 |
| 代理机构 |
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代理人 |
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| 地址 |
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