| 摘要 |
Disclosed is a pharmaceutical formulation for absorption through oral mucosae comprising and effective amount of (a) a pharmaceutical agent in mixed micellar form, (b) at least one micelle-forming compound selected from the group comprising an alkali metal alkyl sulphate and a polyoxyethylene sorbitan monooleate, (c) a block copolymer of polyoxyethylene and polyoxypropylene, (d) at least one additional micelle-forming compound chosen from the group comprising trihydroxyoxocholanyl glycine and salts thereof, glycerin, polyglycerin, lecithin, hyaluronic acid, glycolic acid, lactic acid, chamomile extract, cucumber extract, oleic acid, linoleic acid, linolenic acid, monolein, monooleates, monolaurates, borage oil, evening primrose oil, menthol, polyglycerin, lysine, polylysine, triolein, polyoxyethylenen ethers, polidocanol alkyl ethers, chenodeoxycholate, deoxycholate, alkali metal salicylate, pharmaceutically acceptable edetate, and pharmaceutically acceptable salts, and (e) a suitable solvent.
|
