| 发明名称 |
DIAGNOSIS AND TREATMENT OF CARDIAC DISORDERS |
| 摘要 |
Nitric oxide synthase deficiency causes diminished ryanodine receptor S-nitrosylation leading to increased diastolic calcium (Ca2+) and reduced intra sarcoplasmic reticulum calcium (Ca2+) content. Compositions for treatment of cardiac failure and cardiac disorders such as arrhythmias and sudden cardiac death are described.
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| 申请公布号 |
US2010316622(A1) |
申请公布日期 |
2010.12.16 |
| 申请号 |
US20080740395 |
申请日期 |
2008.11.03 |
| 申请人 |
UNIVERSITY OF MIAMI |
发明人 |
HARE JOSHUA M.;GONZALEZ DANIEL |
| 分类号 |
A61K38/44;A61K31/13;A61K31/502;A61K31/519;A61K31/7088;A61K31/713;A61K38/02;A61P9/00;C12N5/10;C12N15/63;C12Q1/26;C12Q1/68;G01N33/53 |
主分类号 |
A61K38/44 |
| 代理机构 |
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