发明名称 |
Oligomer-Tricyclic Conjugates |
摘要 |
The invention provides small molecule drugs that are chemically modified by covalent attachment of a water soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the small molecule drug not attached to the water soluble oligomer. |
申请公布号 |
US2010298296(A1) |
申请公布日期 |
2010.11.25 |
申请号 |
US20080744467 |
申请日期 |
2008.11.28 |
申请人 |
NEKTAR THERAPEUTICS |
发明人 |
ZHANG WEN;GU XUYUAN;ALLUMS STEPHANIE;RIGGS-SAUTHIER JENNIFER |
分类号 |
A61K31/55;A61K31/137;A61K31/335;A61P29/00;C07C211/32;C07D223/24;C07D313/12 |
主分类号 |
A61K31/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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