发明名称 [(4-OXO-4H-CHROMEN-3-YL)-HYDROXY METHYL]- OR [(4-OXO-4H-CHROMEN-3-YL)-METHYL]-PHOSPHONIC ACID DERIVATES
摘要 [(4-Oxo-4H-chromen-3-yl)-hydroxymethyl]- or [(4-oxo-4H-chromen-3-yl)-methyl]-phosphoric acid derivatives (I) and their salts, are new. [(4-Oxo-4H-chromen-3-yl)-hydroxymethyl]- or [(4-oxo-4H-chromen-3-yl)-methyl]-phosphoric acid derivatives of formula (I) and their salts, are new. R 1>, R 3>H, OH or 1-8C alkoxy; R 4>H, 1-4C alkyl, OH or 1-8C alkoxy; R 5>H or OH (preferred); and R 6>H or 1-18C alkyl. Where R 1>-R 4> is not hydrogen at the same time. Independent claims are included for: (1) the preparations of (I); and (2) a preparation containing (I). [Image] ACTIVITY : Nootropic; Dermatological. MECHANISM OF ACTION : Histidinde-carboxylase inhibitor; Protein inhibitor; Elastase inhibitor; Aldosereductase hyaluronidase inhibitor.
申请公布号 EP2134732(B1) 申请公布日期 2010.11.24
申请号 EP20070818668 申请日期 2007.10.04
申请人 MERCK PATENT GMBH 发明人 CAROLA, CHRISTOPHE;BUCHHOLZ, HERWIG
分类号 C07F9/655 主分类号 C07F9/655
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