METHOD OF DETERMINING THE PERSONALIZED DOSE OF TALNIFLUMATE BY SINGLE NUCLEOTIDE POLYMORPHISM ANALYSIS AND GENE FOR USE THEREIN

摘要

PURPOSE: A method for determining administration of talniflumate by SNP analysis and a gene used for the same are provided to determine proper administration amount of talniflumate by analyzing the relation of pharmacodynamic parameter and SNP. CONSTITUTION: A method for determining Cmax(maximum plasma concentration) of talniflumate by SNP comprises: a step of collecting biological sample from an individual; a step of analyzing gene of biological sample using SNP chip and identifying genotype thereof; a step of determining Cmax in a value indicated in each line of M1 row in case that the genotype of SNP is indicated in G1 row of figure 1a-1j; and a step of determining Cmax in a value indicated in each line of figure 1a-1j in case that the genotype of SNP is indicated in each line of G3 row of figure 1a-1j.