The present invention provides a method of decreasing the level of ubiquitylated protein in a subject, the method comprising administering a heterocyclic compound disclosed herein or a pharmaceutically acceptable salt, hydrate or prodrug thereof to a subject in need thereof.
申请公布号
CA2761049(A1)
申请公布日期
2010.11.18
申请号
CA20102761049
申请日期
2010.05.11
申请人
THE REGENTS OF THE UNIVERISTY OF CALIFORNIA;ZENYAKU KOGYO KABUSHIKIKAISHA
发明人
GREEN, KIM NICHOLAS;WEBER, ECKARD;OLTERSDORF, TILMAN;ROGERS, SHARON;LAFERLA, FRANK