METHODS OF PREVENTING ISCHEMIC INJURY USING PERIPHERAL NOCICEPTIVE STIMULATION
摘要
<p>Methods of inhibiting ischemia-related and ischemia-reperfusion- related injury are provided. Remote administration of a C-fiber activator or TRPV1 agonist or remote electrical stimulation and activation of TRPV1 reduces ischemia-related tissue damage in subjects at risk for Ischemia-related tissue damage, in aspects of the invention, remote application of a TRPV1 agonist inhibits ischemia-related cardiac tissue damage. Methods of inhibiting cardiac tissue damage by topically administering the TRPV1 agonist, capsaicin are provided.</p>
申请公布号
WO2010129845(A1)
申请公布日期
2010.11.11
申请号
WO2010US33993
申请日期
2010.05.07
申请人
UNIVERSITY OF CINCINNATI;JONES, W., KEITH;REN, XIAOPING;WEINTRAUB, NEAL, LEE
发明人
JONES, W., KEITH;REN, XIAOPING;WEINTRAUB, NEAL, LEE