发明名称 |
ANTAGONISTS OF PGD2 RECEPTORS |
摘要 |
Described herein are compounds and pharmaceutical compositions containing such compounds that antagonize the PGD2 activated chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2). Also described herein are methods of using such CRTH2 antagonists, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2 mediated conditions or diseases.
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申请公布号 |
US2010280049(A1) |
申请公布日期 |
2010.11.04 |
申请号 |
US20080741808 |
申请日期 |
2008.10.31 |
申请人 |
AMIRA PHARMACEUTICALS, INC. |
发明人 |
STEARNS BRIAN ANDREW;TRUONG YEN PHAM;HUTCHINSON JOHN HOWARD |
分类号 |
A61K31/4965;A61K31/438;A61K31/519;A61P1/00;A61P7/00;A61P9/10;A61P11/00;A61P11/02;A61P11/06;A61P11/08;A61P17/00;A61P17/06;A61P19/02;A61P25/00;A61P35/00;A61P37/08;C07D471/04;C07D471/10;C07D487/04 |
主分类号 |
A61K31/4965 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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