发明名称 |
ALPHA-LIPOIC ACID NANOPARTICLE AND METHOD FOR PRODUCING THE SAME |
摘要 |
<p>Provision of a stable ±-lipoic acid. A method for producing ±-lipoic acid nanoparticles, the method comprising the steps of: preparing an aqueous dispersion liquid containing ±-lipoic acid and a nonionic surfactant; adding a divalent metal salt into the aqueous dispersion liquid, wherein the divalent metal salt is a divalent metal halide, a divalent metal acetate or a divalent metal gluconate; and adding an alkali metal carbonate or an alkali metal phosphate into the aqueous dispersion liquid which has been added with the divalent metal salt, thereby forming ±-lipoic acid nanoparticles.</p> |
申请公布号 |
EP2241314(A1) |
申请公布日期 |
2010.10.20 |
申请号 |
EP20080863352 |
申请日期 |
2008.12.12 |
申请人 |
EZAKI GLICO CO., LTD.;NANOEGG RESEARCH LABORATORIES, INC. |
发明人 |
SUGIMOTO, KAZUHISA;NISHIURA, HIROMI;YAMAGUCHI, YOKO;HIRATA, KEIICHI;KUBOTA, YOSHIKI |
分类号 |
A61K31/385;A61K47/02;A61K47/34;A61P1/02;A61P17/00;A61P39/06;B82Y5/00;C07D339/04 |
主分类号 |
A61K31/385 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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