The invention provides human engineered antibodies, antigen-binding fragments thereof, that bind to, and inhibit the activity of, human DKK-1, and which are effective in treating diseases in which pathogenesis is mediated by DKK-1.
申请公布号
WO2010117980(A1)
申请公布日期
2010.10.14
申请号
WO2010US30039
申请日期
2010.04.06
申请人
ELI LILLY AND COMPANY;CHEDID, MARCIO;DARLING, RYAN, JAMES;GALVIN, RACHELLE, JEANETTE;SWANSON, BARBARA, ANNE
发明人
CHEDID, MARCIO;DARLING, RYAN, JAMES;GALVIN, RACHELLE, JEANETTE;SWANSON, BARBARA, ANNE
