发明名称 |
NOVEL SALT OF 1,3,5-TRIAZINE-2,4,6-TRIAMINE DERIVATIVE |
摘要 |
Anytime obtained is uniform crystal of N-(4--fluorophenyl)-N'-phenyl-N"-(pyrimidin-2-ylmethyl)-1,3,5--triazine-2,4,6-triamine (compound A) and/or N,N'-bis(4--fluorophenyl)-N"-(pyrimidin-2-ylmethyl)- 1,3,5-triazine-2,4,6-triamine (compound B) as a medicament or a starting material for the preparation of the medicament, and provided are a fumarate of the compound A and/or the compound B having excellent stability and a novel crystal thereof. A salt of the compound A and/or the compound B with fumaric acid enables uniform crystal to be anytime obtained, and thus, it is a compound that is very useful as a medicament or a starting material for the preparation of the medicament having excellent stability.
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申请公布号 |
CA2660954(A1) |
申请公布日期 |
2010.09.30 |
申请号 |
CA20092660954 |
申请日期 |
2009.03.31 |
申请人 |
ASTELLAS PHARMA INC. |
发明人 |
OHMORI, JUNYA;KASAI, MAKOTO;KIMURA, TAKENORI;HAMADA, NORITAKA;MIZOGUCHI, RYO;MIYAMOTO, SATOSHI;KAWANO, NORIYUKI |
分类号 |
C07D403/12;A61K31/194;A61K31/53;C07C57/15 |
主分类号 |
C07D403/12 |
代理机构 |
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主权项 |
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