发明名称 NOVEL SALT OF 1,3,5-TRIAZINE-2,4,6-TRIAMINE DERIVATIVE
摘要 Anytime obtained is uniform crystal of N-(4--fluorophenyl)-N'-phenyl-N"-(pyrimidin-2-ylmethyl)-1,3,5--triazine-2,4,6-triamine (compound A) and/or N,N'-bis(4--fluorophenyl)-N"-(pyrimidin-2-ylmethyl)- 1,3,5-triazine-2,4,6-triamine (compound B) as a medicament or a starting material for the preparation of the medicament, and provided are a fumarate of the compound A and/or the compound B having excellent stability and a novel crystal thereof. A salt of the compound A and/or the compound B with fumaric acid enables uniform crystal to be anytime obtained, and thus, it is a compound that is very useful as a medicament or a starting material for the preparation of the medicament having excellent stability.
申请公布号 CA2660954(A1) 申请公布日期 2010.09.30
申请号 CA20092660954 申请日期 2009.03.31
申请人 ASTELLAS PHARMA INC. 发明人 OHMORI, JUNYA;KASAI, MAKOTO;KIMURA, TAKENORI;HAMADA, NORITAKA;MIZOGUCHI, RYO;MIYAMOTO, SATOSHI;KAWANO, NORIYUKI
分类号 C07D403/12;A61K31/194;A61K31/53;C07C57/15 主分类号 C07D403/12
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