NOVEL 2-DEOXY-SCYLLO-INOSOSE SYNTHASE

摘要

Disclosed is a DOI synthase having superior properties including stability to heat and pH compared to those of conventional enzymes. Also disclosed is a process for producing DOI using the enzyme. Specifically disclosed is a 2-deoxy-scyllo-inosose synthase having the properties (1), (2), (4), (6) and (7) mentioned below and also having the property (3) and/or (5) mentioned below. (1) Activity: the enzyme has a function of converting glucose-6-phosphate into 2-deoxy-scyllo-inosose. (2) Optimum pH range: 7.0 to 7.7. (3) Stable pH range: 6.0 to 8.0. (4) Optimum temperature range: 55 to 70°C. (5) Stable temperature range: 20 to 46°C. (6) Coenzyme: NAD+ is utilized. (7) Molecular weight : 39000 to 42000.