| 摘要 |
PROBLEM TO BE SOLVED: To provide novel synthetic routes, which are highly applicable to industrial preparation of therapeutically beneficial oxidized phospholipids. SOLUTION: A reacting mixture which comprises compounds having a glycerolic backbone and one or more oxidized moieties attached to the glycerolic backbone through an ether bond is produced by reacting a compound having the glycerolic backbone and one or more free hydroxyl groups with a compound having one or more oxidized moieties. Particularly, disclosed are methods of introducing phosphorous-containing moieties such as phosphate moieties to compounds having glycerolic backbone. COPYRIGHT: (C)2010,JPO&INPIT
|
