摘要 |
<P>PROBLEM TO BE SOLVED: To provide a modified substrate, having a hydrophilic polymer immobilized on a substrate surface and ensuring high blood compatibility, and a process for producing the same. <P>SOLUTION: This modified substrate includes a hydrophilic polymer in which the amount of soluble hydrophilic polymers contained is 15 wt.% or less, and to which the sticking of human platelets amounts to 10 platelets/4.3×10<SP>3</SP>μm<SP>2</SP>or less. This process for producing the modified substrate includes a step of exposing to radiation a substrate while in contact with an aqueous solution containing a hydrophilic polymer and an antioxidant. Thus, the modified substrate having a hydrophilic polymer immobilized on the substrate surface, and ensuring high blood compatibility, and the process for producing the same are provided. <P>COPYRIGHT: (C)2010,JPO&INPIT |