发明名称 USE OF THE PROTIEN MABA (FABG1) OF MYCOBACTERIUM TUBERCULOSIS FOR DESIGNING AND SCREENING ANTIBIOTICS
摘要 The protein MabA, also named protein FabG1, which is recombinant in a purified form, or the recombinant proteins derived from the protein MabA by mutation of at least one amino acid. The uses of proteins MabA, or recombinant proteins derived from protein MabA by mutation of at lease one amino acid, proteins and to the crystalloghraphis co-ordinates thereof, in terms of the implementation of methods for designing and screening ligands of these proteins, and advantageously, ligands inhibiting the enzymatic activity of these proteins.
申请公布号 US2010240084(A1) 申请公布日期 2010.09.23
申请号 US20090423586 申请日期 2009.04.14
申请人 CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);UNIVERSITE DE MONTPELLIER 1 发明人 QUEMARD ANNAIK;LABESSE GILLES;DAFFE MAMADOU;MARRAKCHI HEDIA;DOUGUET DOMINIQUE;COHEN-GONSAUD MARTIN;DUCASSE STEPHANIE
分类号 C12Q1/26;C07H21/00;C07K14/35;C12N1/21;C12N9/02;C12N15/53;C12N15/74 主分类号 C12Q1/26
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