The present invention relates to inhibitors of ROCK1 and ROCK2, which may be selective for ROCK2, and methods of modulating the pharmacokinetic and/or pharmacodynamic properties of such compounds. Also provided are methods of inhibiting ROCK1 and/or ROCK2. Also provided are treatments combining inhibitors of ROCK1 and/or ROCK2 with statins.
申请公布号
CA2755095(A1)
申请公布日期
2010.09.16
申请号
CA20102755095
申请日期
2010.03.09
申请人
SURFACE LOGIX, INC.
发明人
SWEETNAM, PAUL;BARTOLOZZI, ALESSANDRA;CAMPBELL, ANTHONY;COLE, BRIDGET;FOUDOULAKIS, HOPE;KIRK, BRIAN;SESHADRI, HEMALATHA;RAM, SIYA
