发明名称 HETEROARYL CARBOXAMIDES
摘要 The invention relates to novel heteroaryl carboxamides of formula (I) and salts, hydrates or solvates thereof, processes for their preparation, and their use for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory. (see formula I) In formula (I), R1 is an azabicyclo[m.n.o]alkyl radical having 7 to 11 ring atoms, in which m, n and o are identical or different and are 0, 1, 2 or 3, and where the radical is optionally substituted by (C1-C6)-alkyl; the ring A is pyrimido, or is optionally benzo-fused pyrido, pyridazo or pyrazino; and R2 and R3 are identical or different radicals, wherein the radical is hydrogen, halogen, formyl, carbamoyl, cyano, trifluoromethyl, trifluoromethoxy, nitro, (C1-C6(-alkyl, (C1-C6)-alkoxy, (C1-C6)-alkylthio, (C3-C8)-cycloalkyl, 4- to 8-membered heterocyclyl, phenyl or 5-to 6-membered heteroaryl, where phenyl and heteroaryl are optionally substituted by halogen, (C1-C4)-alkyl, (C1-C4)-alkoxy, amino, mono- or di-(C1-C4)-alkylamino, (C1-C4)-alkanoylamino or (C1-C4)-alkanesulfonylamino.
申请公布号 CA2467367(C) 申请公布日期 2010.09.14
申请号 CA20022467367 申请日期 2002.11.06
申请人 BAYER HEALTHCARE AG 发明人 HENDRIX, MARTIN;BOESS, FRANK-GERHARD;ERB, CHRISTINA;KRUEGER, JOACHIM;LUITHLE, JOACHIM;METHFESSEL, CHRISTOPH;SCHREIBER, RUDY;WIESE, WELF-BURKHARD
分类号 C07D215/48;A61K31/47;A61K31/517;A61P25/28;C07D241/46;C07D453/02;C07D463/04 主分类号 C07D215/48
代理机构 代理人
主权项
地址