发明名称
摘要 The present disclosure relates to a bi-specific antibody or antibody fragment having at least one arm that is reactive against a targeted tissue and at least one other arm that is reactive against a linker moiety. The linker moiety encompasses a hapten to which antibodies have been prepared. The antigenic linker is conjugated to one or more therapeutic or diagnostic agents or enzymes. The disclosure provides constructs and methods for producing the bi-specific antibodies or antibody fragments, as well as methods for using them.
申请公布号 JP4538062(B2) 申请公布日期 2010.09.08
申请号 JP20080158796 申请日期 2008.06.18
申请人 发明人
分类号 C12N15/09;G01R33/28;A61B5/055;A61K39/395;A61K49/00;A61K51/00;A61K51/08;A61K51/10;A61P35/00;C07K5/107;C07K5/11;C07K16/18;C07K16/28;C07K16/30;C07K16/44;C07K16/46;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12P21/08;C12Q1/68;G01N33/50;G01N33/574;G01N33/577 主分类号 C12N15/09
代理机构 代理人
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