<p>Materials and method for treating cancer and screening for anti-neoplastic agents are provided. These materials and methods can include sphingosine 1-phosphate antagonists that bind to sphingosine-1 phosphate receptor subtype 3. Antibodies and aptamers that selectively bind to an epitope in the extracellular loop between transmembrane domains two and three of sphingosine-1-phosphate receptor subtype 3 are provided.</p>
申请公布号
WO2010098781(A1)
申请公布日期
2010.09.02
申请号
WO2009US45274
申请日期
2009.05.27
申请人
EXPRESSION DRUG DESIGNS, LLC;HERR, DERON, R.;HARRIS, GREG, L.