发明名称 FUSED HETEROCYCLIC DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND MEDICINAL USE THEREOF
摘要 The present invention provides a compound useful as an agent for the prevention or treatment of a sex hormone-dependent disease or the like. That is, the present invention provides a fused heterocyclic derivative represented by the following general formula (I), a pharmaceutical composition containing the same, a medicinal use thereof and the like. In the formula (I), ring A represents 5-membered cyclic unsaturated hydrocarbon or 5-membered heteroaryl; R A represents halogen, alkyl, alkenyl, alkynyl, carboxy, alkoxy, carbamoyl, alkylcarbamoyl or the like; ring B represents aryl or heteroaryl; R B represents halogen, alkyl, carboxy, alkoxy, carbamoyl, alkylcarbamoyl or the like; E 1 and E 2 represent an oxygen atom or the like; U represents a single bond or alkylene; X represents a group represented by Y, -SO 2 -Y, -O-(alkylene)-Y, -O-Z in which Y represents Z, amino or the like; Z represents cycloalkyl, heterocycloalkyl, aryl, heteroaryl or the like; or the like.
申请公布号 EP1939204(A4) 申请公布日期 2010.09.01
申请号 EP20060811925 申请日期 2006.10.17
申请人 KISSEI PHARMACEUTICAL CO., LTD. 发明人 OHNO, KOHSUKE;MIYAGI, TAKASHI;OZAWA, TOMONAGA;FUSHIMI, NOBUHIKO
分类号 C07D487/04;A61K31/519;A61K31/55;A61K45/00;A61P13/08;A61P15/00;A61P15/18;A61P17/02;A61P17/10;A61P17/14;A61P19/00;A61P25/20;A61P25/28;A61P35/00;A61P43/00;C07D495/04 主分类号 C07D487/04
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