| 发明名称 |
Oligonucleotide compositions with enhanced efficiency |
| 摘要 |
The oliginucleotide compositions of the present invention make use of combinations of oligonucleotides. In one aspect, the invention features an oligonucleotide composition including at least 2 different oligonucleotides targeted to a target gene. This invention also provides methods of inhibiting protein synthesis in a cell and methods of identifying oligonucleotide compositions that inhibit synthesis of a protein in a cell. |
| 申请公布号 |
EP2221377(A1) |
申请公布日期 |
2010.08.25 |
| 申请号 |
EP20100151247 |
申请日期 |
2003.02.03 |
| 申请人 |
LIFE TECHNOLOGIES CORPORATION |
发明人 |
WOOLF, TOD M.;TAYLOR, MARGARET F. |
| 分类号 |
C12N15/09;A61K31/713;A61K48/00;A61P1/04;A61P9/00;A61P17/06;A61P27/02;A61P29/00;A61P31/12;A61P31/18;A61P31/20;A61P35/00;A61P37/02;A61P43/00;C07H19/00;C07H21/02;C07H21/04;C12N;C12N15/00;C12N15/113 |
主分类号 |
C12N15/09 |
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