发明名称 METHOD OF TREATING LUPOUS
摘要 FIELD: medicine. ^ SUBSTANCE: group of inventions refers to medicine, namely to immunology and can be used in treating lupous nephritis (LN). A method according to the invention involves the first introduction of CD20-antibody to an individual in amount 0.5 to 4 g, then the second introduction of antibody 16-54 weeks later in amount 0.5 to 4 g. Thus every time antibody is introduced to an individual in the form of a single dose or in the form of two or three separate doses of antibody. Besides the group of inventions includes application of CD20-antibody for preparing a drug for LN treatment and a product containing a CD20-antibody container and a leaflet with lupous nephritis treatment instructions. ^ EFFECT: use of the inventions allows lowering intensity of manifested symptoms of LN due to suppression of B-cell activity ensured by the effect of CD20-antibody. ^ 20 cl, 2 tbl, 6 dwg, 3 ex
申请公布号 RU2396980(C2) 申请公布日期 2010.08.20
申请号 RU20060146927 申请日期 2005.06.02
申请人 DZHENENTEK, INK. 发明人 BRUNETTA POL DZH.
分类号 A61K;A61K39/395;A61P37/00;C07K16/28 主分类号 A61K
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