| 发明名称 |
VERBESSERTE SYNTHESE VON (2S-CIS)-2-(BROMMETHYL)- 2-(4-CHLORPHENYL)-1,3-DIOXOLAN-4-METHANOL- METHANSULFONAT(ESTER) |
| 摘要 |
The present invention relates to an improved process for the preparation of (2S-cis)-2-(bromomethyl)-2-(4-chlorophenyl)-1,3-dioxolane-4-methanol methanesulfonate(ester), a key intermediate for the preparation of the apoB secretion/MTP inhibitor mitratapide. |
| 申请公布号 |
AT474836(T) |
申请公布日期 |
2010.08.15 |
| 申请号 |
AT20080759956T |
申请日期 |
2008.05.23 |
| 申请人 |
JANSSEN PHARMACEUTICA, N.V. |
发明人 |
FILLIERS, WALTER FERDINAND MARIA;VERSTAPPEN, WALTER LOUIS ANTOINE;BELLINKX, RONNY |
| 分类号 |
C07D405/14 |
主分类号 |
C07D405/14 |
| 代理机构 |
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