COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS

摘要

The invention provides a novel class of 2,7-naphthyridin derivatives; pharmaceutical compositions comprising such compounds and methods of using such compounds to treat o prevent diseases or disorders associated with abnormal or deregulated kinase activity,particulary Syk,ZAP70,KDR,FMS,FLT3,c-Kit,RET,TrkA,TrkB,TrkC-GR-1R,Alk,c- FMS.or combinations thereof.