发明名称 |
UNIVERSAL CARRIER FOR TARGETING MOLECULES TO Gb3 RECEPTOR EXPRESSING CELLS |
摘要 |
The present invention concerns an universal polypeptidic carrier for targeting directly or indirectly a molecule to Gb3 receptor expressing cells and having the following formula STxB-Z(n)-Cys, wherein:—STxB is the Shiga Toxin B subunit or a functional equivalent thereof, Z is an amino-acid devoided of sulfydryl group, n being 0, 1 or a polypeptide, Cys is the amino-acid Cysteine, and the use thereof for MHC class I and MHC class II presentation of antigens. |
申请公布号 |
US2010196418(A1) |
申请公布日期 |
2010.08.05 |
申请号 |
US20090569007 |
申请日期 |
2009.09.29 |
申请人 |
JOHANNES LUDGER;TARTOUR ERIC;GOUD BRUNO;FRIDMAN WOLF HERVE |
发明人 |
JOHANNES LUDGER;TARTOUR ERIC;GOUD BRUNO;FRIDMAN WOLF HERVE |
分类号 |
A61K39/385;C12N15/00;A61K31/7088;A61K38/00;A61K38/16;A61K47/48;A61K48/00;A61P35/00;A61P37/04;A61P43/00;C07H21/00;C07K1/16;C07K14/25;C07K17/00;C07K19/00;C12N1/21;C12N5/071;C12N15/31;C12N15/66;C12N15/74;C12P21/00;C12Q1/68 |
主分类号 |
A61K39/385 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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