发明名称 PROTEINASE-ENGINEERED CANCER VACCINE INDUCES IMMUNE RESPONSES TO PREVENT CANCER AND TO SYSTEMICALLY KILL CANCER CELLS
摘要 <p>A harmless cancer vaccine is made from cancer cells with extracellular proteins including self-recognition molecular patterns being digested by a proteinase. The cancer vaccine is used to vaccinate an individual to induce immune responses against cancer cells systemically. Cancer cells become harmless when they are digested by TumoraseTM. Some proteinases including trypsin cannot kill cancer cells completely and treated cancer cells need to be further processed in order to be harmless and effective. Cancer cells may be from tissue-cultured human or animal cancer cell lines or cancer patients directly. Cancer vaccine vaccinated individuals produce cancer vaccine specific immune responses against cancer cells. Immune response components may be isolated and used to fight against cancer for a cancer patient with a suppressed immune system. Cancer vaccine specific immune components may include cancer vaccine specific polyclonal antibodies, B-cells, T-cells, natural killer cells, monocytes, macrophages and other lymphocytes.</p>
申请公布号 WO2010086709(A1) 申请公布日期 2010.08.05
申请号 WO2010IB00138 申请日期 2010.01.28
申请人 QIAN, YONG 发明人 QIAN, YONG
分类号 A61K31/445;A61K31/44;A61K38/55;A61K39/00;A61P35/00 主分类号 A61K31/445
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