发明名称 COMBINATIONS OF PHOSPHOINOSITIDE 3-KINASE INHIBITOR COMPOUNDS AND CHEMOTHERAPEUTIC AGENTS, AND METHODS OF USE
摘要 Combinations of PI3K inhibitor compounds having Formulas and and chemotherapeutic agents, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for treating hyperproliferative disorders such as cancer. Methods of using such combinations for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
申请公布号 KR20100085912(A) 申请公布日期 2010.07.29
申请号 KR20107007940 申请日期 2008.09.10
申请人 GENENTECH, INC.;F. HOFFMANN-LA ROCHE AG 发明人 BELVIN MARCIA;FRIEDMAN LORI;HOEFLICH KLAUS;SAMPATH DEEPAK;VIJAPURKAR ULKA;WALLIN JEFFREY;JOHNSON LEISA;SINGH MALLIKA;PATEL SONAL
分类号 A61K31/505;A61P35/00;G01N33/50 主分类号 A61K31/505
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