METHODS FOR TREATING DISORDERS ASSOCIATED WITH HYPERLIPIDEMIA IN A MAMMAL

摘要

The disclosure is directed to methods for treating hyperlipidemia in a mammal, e.g. by administering an MTP inhibitor and an omega-3 fatty acid (for example, fish oil). Co¬ administration of the MTP inhibitor with the omega-3 fatty acid produces a therapeutic benefit, for example, a reduction in the concentration of cholesterol and/or triglycerides in the blood stream, but with fewer or reduced side effects than when higher dosages of the MTP inhibitor are used during monotherapy to provide the same or similar therapeutic benefit.