发明名称 |
Radiolabeled cannabinoid-1 receptor modulators |
摘要 |
The present invention relates to particular radiolabeled Cannabinoid-1 (CB1) receptor modulators, and methods of using these modulators for labeling and diagnostic imaging of Cannabinoid-1 receptors in mammals, particularly humans. In addition, intermediates useful for the synthesis of the radiolabeled Cannabinoid-1 receptor modulators are also disclosed, as well as the processes for synthesizing the radiolabeled Cannabinoid-1 receptor modulators. Still further, formulations of the radiolabeled Cannabinoid-1 receptor compounds are described.
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申请公布号 |
US7754188(B2) |
申请公布日期 |
2010.07.13 |
申请号 |
US20050559228 |
申请日期 |
2005.12.06 |
申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
BURNS H. DONALD;CHEN ALEX M.;GIBSON RAYMOND E.;GOULET MARK T.;HAGMANN WILLIAM K.;HAMILL TERENCE G.;JEWELL JAMES P.;LIN LINUS S.;LIU PING;PERESYPKIN ANDREY V. |
分类号 |
A61K51/00;A61K51/04;A61M36/14;C07D213/64;C07D239/34 |
主分类号 |
A61K51/00 |
代理机构 |
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地址 |
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