发明名称 Method of enantioselective nucleophilic addition reaction of enamide to imine and synthesis method ofα-amino-γ-keto acid ester
摘要 An asymmetric synthesis of amino acid compound that is useful as a starting material or synthetic intermediate for production of medicinal products, agrichemicals, perfumes, functional polymers, etc. There is provided a method of enanthio-selective nucleophilic addition reaction to imine compound being a method of nucleophilic addition reaction of enamide compound accompanied by amino formation to imino group (—CH═N—) of imine compound, characterized in that the reaction is performed in the presence of a chiral copper catalyst. Further, there is provided a novel method of synthesizing an amino acid compound, etc., to which the above is applied.
申请公布号 US7754898(B2) 申请公布日期 2010.07.13
申请号 US20040587075 申请日期 2004.01.25
申请人 JAPAN SCIENCE AND TECHNOLOGY AGENCY 发明人 KOBAYASHI SHU
分类号 C07D207/14;B01J31/22;C07B53/00;C07B61/00;C07C229/00;C07C231/12;C07C231/18;C07C233/47;C07C237/00;C07C269/06;C07C271/22;C07D207/273 主分类号 C07D207/14
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