发明名称 ANTI-PD-L1 ANTIBODIES AND THEIR USE TO ENHANCE T-CELL FUNCTION
摘要 The present application relates to anti-PD-L1 antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use enhance T-cell function to upregulate cell-mediated immune responses and for the treatment of T cell dysfunctional disorders, including infection (e.g., acute and chronic) and tumor immunity.
申请公布号 WO2010077634(A1) 申请公布日期 2010.07.08
申请号 WO2009US67104 申请日期 2009.12.08
申请人 GENENTECH, INC.;IRVING, BRYAN;CHEUNG, JEANNE;CHIU, HENRY;LEHAR, SOPHIE, M.;MAECKER, HEATHER;MARIATHASAN, SANJEEV;WU, YAN 发明人 IRVING, BRYAN;CHEUNG, JEANNE;CHIU, HENRY;LEHAR, SOPHIE, M.;MAECKER, HEATHER;MARIATHASAN, SANJEEV;WU, YAN
分类号 C07K16/28;A61K39/395;A61P35/00 主分类号 C07K16/28
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