摘要 |
The present application relates to anti-PD-L1 antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use enhance T-cell function to upregulate cell-mediated immune responses and for the treatment of T cell dysfunctional disorders, including infection (e.g., acute and chronic) and tumor immunity. |
申请人 |
GENENTECH, INC.;IRVING, BRYAN;CHEUNG, JEANNE;CHIU, HENRY;LEHAR, SOPHIE, M.;MAECKER, HEATHER;MARIATHASAN, SANJEEV;WU, YAN |
发明人 |
IRVING, BRYAN;CHEUNG, JEANNE;CHIU, HENRY;LEHAR, SOPHIE, M.;MAECKER, HEATHER;MARIATHASAN, SANJEEV;WU, YAN |