| 发明名称 |
p53 wild-type as biomarker for the treatment with mTOR inhibitors in combination with a cytotoxic agent |
| 摘要 |
Provided are biomarkers for determining the sensitivity of proliferative diseases such as cancer to therapeutic agents, in particular mTOR inhibitors in combination with a cytotoxic agent, in particular a cytotoxic agent which damages or affects the integrity of DNA.
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| 申请公布号 |
US7749698(B2) |
申请公布日期 |
2010.07.06 |
| 申请号 |
US20050590406 |
申请日期 |
2005.02.22 |
| 申请人 |
NOVARTIS AG |
发明人 |
BEUVINK IWAN;BOULAY ANNE;LANE HEIDI;O'REILLY TERENCE;THOMAS GEORGE |
| 分类号 |
C12Q1/68;G01N33/53;G01N33/574 |
主分类号 |
C12Q1/68 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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