发明名称 AMINO ACID ESTER PRODRUGS AND THE USE THEREOF
摘要 The invention relates to amino acid ester prodrug derivatives of 2-amino-6-({[2-(4-chlorphenyl)-1,3-oxazol-4-yl]methyl}sulfanyl)4-(4-{[2,3-dihydroxypropyl]oxy}phenyl)pyridine- 3,5-dicarbonitriles of formula (I), where RA is hydrogen or methyl, and RPD is a group of the formulas (II) or (III), wherein # is the linking site having each O atom, to a method for the production thereof, to the use thereof for treating and/or preventing illnesses, and to the use thereof for producing pharmaceuticals for treating and/or preventing illnesses, particularly of cardiovascular diseases.
申请公布号 CA2746727(A1) 申请公布日期 2010.07.01
申请号 CA20092746727 申请日期 2009.12.03
申请人 BAYER SCHERING PHARMA AKTIENGESELLSCHAFT 发明人 MEIBOM, DANIEL;LERCHEN, HANS-GEORG;VAKALOPOULOS, ALEXANDROS;ALBRECHT-KUEPPER, BARBARA;NELL, PETER;KELDENICH, JOERG;ZIMMERMANN, KATJA;KRENZ, URSULA
分类号 C07D413/12;A61K31/4439 主分类号 C07D413/12
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