发明名称 |
AMINO ACID ESTER PRODRUGS AND THE USE THEREOF |
摘要 |
The invention relates to amino acid ester prodrug derivatives of 2-amino-6-({[2-(4-chlorphenyl)-1,3-oxazol-4-yl]methyl}sulfanyl)4-(4-{[2,3-dihydroxypropyl]oxy}phenyl)pyridine- 3,5-dicarbonitriles of formula (I), where RA is hydrogen or methyl, and RPD is a group of the formulas (II) or (III), wherein # is the linking site having each O atom, to a method for the production thereof, to the use thereof for treating and/or preventing illnesses, and to the use thereof for producing pharmaceuticals for treating and/or preventing illnesses, particularly of cardiovascular diseases.
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申请公布号 |
CA2746727(A1) |
申请公布日期 |
2010.07.01 |
申请号 |
CA20092746727 |
申请日期 |
2009.12.03 |
申请人 |
BAYER SCHERING PHARMA AKTIENGESELLSCHAFT |
发明人 |
MEIBOM, DANIEL;LERCHEN, HANS-GEORG;VAKALOPOULOS, ALEXANDROS;ALBRECHT-KUEPPER, BARBARA;NELL, PETER;KELDENICH, JOERG;ZIMMERMANN, KATJA;KRENZ, URSULA |
分类号 |
C07D413/12;A61K31/4439 |
主分类号 |
C07D413/12 |
代理机构 |
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