| 发明名称 |
IMPROVED GENETIC ELEMENTS PROVIDING HIGH LEVELS OF EXPRESSION |
| 摘要 |
<p>The invention relates to improved genetic elements providing high levels of expression of operably-linked genes in a variety of tissues, In particular, fragments of unmethylated, CpG islands of less than 2kb are shown to provide enhanced transgene expression and have advantages in terms of vector construction and cloning capacity.</p> |
| 申请公布号 |
EP1587934(B1) |
申请公布日期 |
2010.06.23 |
| 申请号 |
EP20040707256 |
申请日期 |
2004.02.02 |
| 申请人 |
MILLIPORE CORPORATION |
发明人 |
WILLIAMS, STEVEN GERAINT;CROMBIE, ROBERT LACHLAN;LIPINSKI, KAI STEFAN;IRVINE, ALISTAIR SIMPSON |
| 分类号 |
C12N15/85;A61K48/00;C12N5/10;C12Q1/68 |
主分类号 |
C12N15/85 |
| 代理机构 |
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