| 发明名称 |
IMPLANT OF AUTOLOGOUS MESENCHYMAL STEM CELLS GENETICALLY MODIFIED FOR BONE REGENERATION AND METHOD FOR THE REPRODUCTION THEREOF. |
| 摘要 |
The present invention develops an implant of two compounds, which comprises mesenchymal stem cells (MSC) transduced into adenoviral non-replicating vectors carrying BMP2 human gene for being used in ex vivo therapy and as demineralized bone matrix, the invention combining the ex vivo genetic therapy and the tissue engineering for developing pre-clinical ossification models.
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| 申请公布号 |
MX2008016103(A) |
申请公布日期 |
2010.06.16 |
| 申请号 |
MX20080016103 |
申请日期 |
2008.12.16 |
| 申请人 |
UNIVERSIDAD AUTONOMA DE NUEVO LEON. |
发明人 |
AUGUSTO ROJAS MARTINEZ;EDUARDO ALVAREZ LOZANO;YANKO CASTRO GOVEA;ROCIO ORTIZ LOPEZ;HERMINIA GUADALUPE MARTINEZ RODRIGUEZ;OSCAR FERNANDO MENDOZA LEMUS;GERARDO RAYMUNDO PADILLA RIVAS;VICTOR HUGO CERVANTES KARDASCH;DANIEL CERVANTES GARCIA;JOSE ALBERTO MORALES DE LOS SANTOS |
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