发明名称 System and process of determining a biological pathway based on a treatment of a biological specimen
摘要 Provided herein is a system and method for analyzing microarray data (transcriptome profiles), metabolite data (metabolome profiles), protein level data (proteome profiles), or any combination thereof to determine the biochemical pathways affected by a treatment. The system and method can be used to generate biochemical pathway information for any organism for which metabolic profile data can be obtained. The system and method may allow users to query the pathways generated and to filter the results of queries based on the -omic profile data, pathways involving molecules of interest, notions of biochemical importance, milestone molecules, and other factors. The system and method may also be suitable for discovery of regulatory sequences in genes. In an exemplary use, the system and method can be utilized to identify three genes involved in “de novo” ammonia “biosynthesis” that are induced by light, and was able to identify a putative cis-element, GWTTGTGG, that is likely involved in the regulation of those genes.
申请公布号 US7739053(B2) 申请公布日期 2010.06.15
申请号 US20050035546 申请日期 2005.01.14
申请人 NEW YORK UNIVERSITY 发明人 PALENCHAR PETER;SHASHA DENNIS;CHOU MICHAEL;REJALI MARC;DORSETT YAIR;KOURANOV ANDREI;CORUZZI GLORIA
分类号 G01N33/48;C12Q1/68;G01N33/50;G06F19/00 主分类号 G01N33/48
代理机构 代理人
主权项
地址